Since 2005 Smack Mellon has been located at 92 Plymouth Street in a former coal-fired boiler house that provided steam for heat and power to several industrial buildings in the neighborhood.

Smack Mellon enables roughly thirty artists each year - 60% of whom are women - to create and present large-scale work to the public in their 6,000 sq ft gallery.

Smack Mellon features a wide range of work, including sculpture, installation art, painting, photography, film/video, and site specific projects.

Previous exhibitions have included the critically acclaimed RESPOND, which was a direct response to the continued failure of the United States to protect its black citizens from police discrimination and violence, after learning of the grand jury's decision to not indict Officer Daniel Pantaleo for the death of Eric Garner.

[5] 2016 Two Solo Exhibitions: Christine Sciulli ROIL and Nona Faustine White Shoes - January 9 - February 21; 2015 Karin Giusti / Michael Kukla - September 26 - December 13; Story of a Story - June 13 - July 26; Art Ready: Selected Work from the Artist Mentorship - May 20–24; Erica Bailey / Yumi Janiaro Roth & Nadine Wasserman - March 14 - April 19; RESPOND - January 17 - February 22 2014 Selin Balci / Tracey Goodman / Alison Owen - December 22 - January 4; Saya Woolfalk / Vandana Jain - September 27- November 9; FOODshed: Art and Agriculture in Action - June 7 - July 27; In Plain Sight - March 15 - April 20; Robert Hickman / Mónika Sziládi - January 18 - March 2 2013 Andrea Loefke / LoVid - November 23 - January 5, 2014; Shana Moulton / Bryan Zanisnik - September 28 - November 3; Art Ready: Selected Work from the Artist Mentorship - May 22 -June 16; The Hollow Center - March 9 April 21; Janet Biggs / Aude Moreau - January 12 - February 24 2012 Adriane Colburn / Cheryl Molnar - September 29 - Nov 4; Art Ready: Selected Work from the Artist Mentorship - June 6 - July 15; Yoko Inoue / Jeanne Quinn - March 17 - April 22; Tamara Gayer / Stephen Sollins / Heeseop Yoon - January 21 - March 4 2011 Rachel Beach / Isidro Blasco - September 24 - October 30; Heat Island - June 18 - July 31; David Henderson / Shannon Plumb - March 5 - April 10; SITE 92 : Work Permit Approved - January 15 - February 20 2010 eteam / Charlotte Schulz - September 25 - November 21; Condensations of the Social - June 19 - August 1;[6] Pawel Wojtasik / Marietta Hoferer - March 6 - April 11; John von Bergen / Michelle Weinstein - January 16 - February 21 2009 Tracey Snelling / Michael Britto - November 21 to January 3; Ellen Driscoll / Fernando Souto - September 26 to November 8; Beauty Underfoot - June 20 to August 2; Blane De St. Croix / Carlos Motta - March 7 to April 12; Kirsten Hassenfeld / Jennie C. Jones - January 17 to February 22 2008 Wayne Hodge / Joanna Malinowska / Jessica Ann Peavy - November 22 to January 4; Sarah Kabot / Shin Il Kim / Kwabena Slaughter - September 27 to November 9; There is No Synonym for Hope - June 14 to July 27; Jennifer Dalton / Rita MacDonald / Amanda C. Mathis - March 8 to April 20; Site 92: Phase II - January 12 to February 24 2007 What is the Artworld Thinking - January 2007 to February 2008; Infinitu et Contini: Repeated Histories, Reinvented Resistance -November 17 to December 30; Peter Dudek / Elana Herzog - September 29 to November 11; Emerging Artists - June 9 to July 22; Ledelle Moe / Letitia Quesenberry - March 24 to April 29; Re-Generation - January 27 to March 11 2006 Legal Aliens - December 2 to January 14, 2007; Mary Temple / Liza McConnell - September 30 to November 12; I Can't Quite Place It... - June 3 to July 16; Mind the Gap - March 18 to April 30; Site 92 - January 21 to March 5 2005 Multiplex 2 - October 14 to November 27; T-Zone - June 4 to July 17; Fifteen Paces - April 2 to May 15; On the Subject of War - February 12 to March 27; Between Interconnectedness - December 4 to January 16 2004 9 x Smack Mellon, 2004 Studio Artists - October 15 to November 14; Sunrise Sunset - June 5 to June 27; Ricoh Gerbl / Robert Taplin - March 20 to May 2; Multiplex - January 24 to March 7 2003 Big Cry Baby - November 8 to December 14; Landslide - September 13 to October 26; Outpost - June 14 to July 20; Custom Fit - April 19 to June 1; Raw - March 1 to April 6 2002 One Hand Clapping - November 30 to December 29; The Omega Manual - October 18 to November 30; Sacred Matter - September 7 to October 6; Hash Brown Potatoes - June 15 to July 21; Flay, Splay, Play - June 7 to July 12; Rendez Vous - April 26 to June 26; Eyestalk - March 9 to April 14 2001 Peppermint - December 1 to January 13; Mir2 - October 18 to November 18; Barnstormers - August 8 to September 23; Popular Mechanics - May 31 to July 8; Simon Lee / Claire Lesteven - April 7 to May 13 2000 Significant Pursuits - November 18 to December 17; Trajectories - September 28 to November 5; White Hot - July 13 to August 20; The Skin Game - April 8 to May 21 1999 Natural Histories - September 25 to November 7; Red Square - May 1 to June 25 1998 Lost and Found - March 20 to May 22; Chiaroscuro - September 12 to October 25; Just Ripe - November 7 to December 20 The Artist Studio Program at Smack Mellon provides urgently needed studio space and career building opportunities to artists wishing to live and work in New York City.