[1][3] The oldest section of the house was built in 1738 by Joshua Humphries.

Samuel Smith, treasurer of the Province of West Jersey, purchased the property in 1766.

During the American Revolutionary War, General Wilhelm von Knyphausen and his Hessian troops occupied the property on the night of June 19, 1778, while retreating from Philadelphia.

British merchant Edward Harris Sr. purchased the property in 1798.

[3][4] The Smith–Cadbury Mansion serves as the headquarters of the Historical Society of Moorestown.