Smoke Run (also spelled as Smokerun) is an unincorporated community in Clearfield County, Pennsylvania, United States.

[1] The community is located along Pennsylvania Route 453, 1.6 miles (2.6 km) west of Ramey.

Smoke Run has a post office with ZIP code 16681.

The town is a rather small town, with a population in the hundreds, a large amount of the people residing within are of Croatian Descent.

This Clearfield County, Pennsylvania state location article is a stub.