Socastee is a census-designated place (CDP) in Horry County, South Carolina, United States.

Socastee is an Indigenous American name referred to as "Sawkastee" in a 1711 land grant to Percival Pawley.

A skirmish between small forces of American and British troops occurred near Socastee Creek in 1781.

By the 1870s, the Socastee community was a significant center for the production and distribution of naval stores such as turpentine and tar.

As of the 2020 United States census, there were 22,213 people, 8,798 households, and 5,903 families residing in the CDP.