Sofades (Greek: Σοφάδες) is a town and municipality in Thessaly, central Greece belonging to the regional unit of Karditsa.

Its 2011 census population was 6,056 people and 18,864 for the municipality, including a large Romani community.

Sofades is located south of Palamas, southwest of Larissa, the capital of Thessaly, northwest of Lamia and southeast of Karditsa and Trikala.

In the early 1800s the English traveler William Martin Leake described the town as an administrative center consisting of around 150 houses and belonging to Abdim Bey of Larissa, but paying a yearly tribute to Ali Pasha.

Chief crops of the region were corn and sesame, from which the oil was a major product.