The Soho Grand Hotel is a hotel located at 310 West Broadway between Grand and Canal Streets in the SoHo neighborhood of Lower Manhattan, New York City at the former location of Church of St. Alphonsus Liguori.

The Soho Grand Hotel opened on August 4, 1996 news of the build initiated significant opposition from local residents; eight prior attempts to build a hotel there in the preceding decade had failed[2] The Soho Grand was designed by David Helpern of Helpern Architects.

[4] The architecture and design incorporate elements including bottle glass and cast iron molding, both of which are prominent in neighborhood buildings from SoHo industrial history.

[6] Soho Grand's guestrooms and Suites’ design direction take their cue from the public spaces.

[7] The Soho Grand has been represented in a variety of feature films, television shows, and online videos including: In fall 2013, a hotel employee started several fires because he allegedly wanted to lighten his workload by making the hotel less popular.