Solomon Sirilio was a child during the expulsion of the Jews from Spain, and wandered with his parents until they eventually reached Thessalonika in Ottoman Greece, where they settled.

His acclaim and renown came on account of a commentary that he wrote on the Jerusalem Talmud, covering the order known as Zeraim and the tractate Sheḳalim.

[6] In Sirilio's introduction to Tractate Berakhot (part ii), he expounds upon the unique style of the Jerusalem Talmud, explaining its peculiar usage of Aramaic words used in the Land of Israel, as opposed to Babylonia, and which have never been elucidated in the Arukh.

[1] A copy of Rabbi Solomon Sirilio's commentary on the Jerusalem Talmud is now stored in the British Museum, which had been purchased by Yehudah Zeraḥya Azulai from his heirs.

[7][4] A different manuscript of Sirilio's commentary is the Moscow Ms., excerpts of which were used in the Oz Vehodor edition, in addition with the British Museum Ms.