Somatostatin receptor

Somatostatin receptors are receptors for the ligand somatostatin, a small neuropeptide associated with neural signaling, particularly in the post-synaptic response to NMDA receptor co-stimulation/activation.

Somatostatin is encoded by a CRE and is very susceptible to gene promoter region activation by transcription factor CREB.

[1] There are five known somatostatin receptors:[2] All are G protein-coupled seven transmembrane receptors.

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Image showing somatostatin biochemical pathway complete with target cell somatostatin receptor