[5] Following his Ph.D., Ghosh started his academic career as an Assistant Professor of Engineering Mechanics at the University of Alabama in 1988.

[5] In 2012, he became the director and lead principal investigator (PI) of an Air Force Center of Excellence in Integrated Materials Modeling.

[8] As President, he established Technical Thrust Areas, or TTAs,[9] to target specific fields of research and advancement for expansion within USACM.

Ghosh has made contributions to the computational study of fatigue and failure in metals and composites with applications in the aerospace, propulsion, automotive and manufacturing industries.

[13] Ghosh's recent research work focuses on additive manufacturing, multifunctional applications like deformable sensors, and life prediction methods.