[18] In May, she won two consecutive singles titles in the third and fourth weeks of the $25k Nottingham events— beating Danielle Lao and Joanna Garland in the finals.

[19][20] During the grass court season, Kartal received wildcards into the main draws at the Surbiton and Ilkley Trophy, and the Nottingham Open.

[24] Kartal was awarded a main draw wildcard at the 2022 Wimbledon Championships, where she made her major debut, losing in the first round to lucky loser Lesley Pattinama Kerkhove, 4–6, 6–3, 1–6.

[25][26][27] In August, she entered US Open qualifying for the first time, but lost in the first round to Spaniard Marina Bassols Ribera in two tiebreak sets.

[29] The following week at the $60k Trvana 2, she upset third seed Daria Snigur in the first round, but was forced to retire from her second-round match due to injury.

[38] In August, Kartal lifted back-to-back ITF W35 GB Pro Series trophies on hardcourts in Roehampton, England, her fourth and fifth titles at that level in the season.

151, having made it through qualifying, she reached the first WTA Tour quarterfinal in her career at the Jasmin Open in Monastir, Tunisia, upsetting fifth seed Jaqueline Cristian, her third Top 100 win of 2024,[41][42] and Mai Hontama.

[43] Next, she defeated Yuliia Starodubtseva in straight sets,[44][45] and then Eva Lys in the semifinals by retirement, to reach her maiden WTA Tour final.

[50][51] Kartal won her sixth ITF title of the year at the W100 Shrewsbury in October, defeating fellow Briton Heather Watson in the final.

[52] Kartal made her Australian Open main-draw debut after securing direct entry thanks to her WTA ranking, but lost in the first round to Jéssica Bouzas Maneiro.