[6][7] Later that year, Caruso originated the role of "Girl" in David Bowie's musical Lazarus at New York Theatre Workshop in Manhattan.

[10] In October 2016, she reprised her role as "Girl" in London in the King's Cross Theatre production of Lazarus for which she received a WhatsOnStage Award nomination for "Best Supporting Actress in a Musical".

The song was produced by Henry Hey, who worked with Caruso as the musical director of Lazarus, and Nick Littlemore of Empire of the Sun.

[18] Caruso was cast to star alongside Sofia Wylie as Sophie in the Netflix fantasy film The School for Good and Evil, an adaptation of the book series by Soman Chainani.

[19][20] In January 2025, was announced that Caruso was cast as Miss Goldenweek for the second season of the Netflix series One Piece, based on the manga of the same name by Eiichiro Oda.