Interview subjects have included Joan Didion, Salman Rushdie, Robert Altman, Brooke Shields, and Norman Mailer.

Included are fashion articles, photos, interviews and more from the first five years of V.[5] In 2016, Lady Gaga was invited to be the guest editor for V for its 99th issue, which features a record-setting sixteen different covers.

In November 2020, ahead of the US elections, V released V127: The "Thought Leaders" Issue, featuring 45 subjects such as Bella Hadid, Mariah Carey, Taylor Swift, Chris Evans, Jaden Smith, Jennifer Lawrence, and more.

Photographed entirely by Dutch fashion photography duo Inez van Lamsweerde and Vinoodh Matadin, the subjects featured within the issue spanned culture, art, and politics, speaking to the American people to exercise their right to vote.

Captured entirely by photographers Inez van Lamsweerde and Vinoodh Matadin in Los Angeles, New York, Mexico and virtually in Korea, a mix of talents ranging from fashion, music, art, literature, and politics all wore CHANEL's Spring-Summer 2021 Ready-To-Wear collection throughout.

In October 2021, American musician and actress Madonna was selected to appear on the cover of V's V133 Winter issue in an homage to Marilyn Monroe and Bern Stern's "The Last Sitting", photographed by Steven Klein.

In addition to the bimonthly print issues, V has released limited-edition monthly calendars, created in collaboration with fashion houses such as GCDS, Guess, Emporio Armani, and EA7.

Some of music, fashion, and the internet's biggest names such as Madison Beer, Finneas, King Princess, Emma Chamberlain, Nicole Richie, Tinashe, Banks, 24kGoldn, and more have joined the podcast.

[10] Some of the celebrities that have been featured on the cover of V Magazine include Britney Spears, Lady Gaga, Lana Del Rey, Selena Gomez, Justin Bieber, Madonna, Katy Perry, Mariah Carey, Christina Aguilera, Gwen Stefani, Janet Jackson, Miley Cyrus, Gwyneth Paltrow, Cameron Diaz, Winona Ryder, Rihanna, Kesha, James Franco, David Beckham, Natalie Portman, Dakota Fanning, Kirsten Dunst, Kristen Stewart, Jennifer Connelly, Swerve Strickland, Nicki Minaj, Kanye West, Orlando Bloom, Demi Moore, Tam Nakano, Beyoncé, Adriana Lima, Dave Meltzer, Marc Jacobs, Salma Hayek, Celine Dion, Dua Lipa, Zack Sabre Jr. and more.