Sophia Cooke (27 February 1814 – 14 September 1895) was a British missionary and schoolmistress at what is now St. Margaret's Secondary School in Singapore.

She arranged church services in Chinese and helped distribute bibles in Malay and Arabic.

Cooke was born in Hilborough in Norfolk and for twenty years she worked as a governess before she was sent to Singapore.

[1] In 1853 the Society for Promotion of Female Education in the East sent Cooke to Singapore to become the Principal of what was then called the "Chinese Girls' School".

The society paid Cooke's salary but she had to rely on fund raising to keep the school viable.