Her first husband was Berthold III, Duke of Zähringen, who was killed in 1122.

Her second husband died in 1129, shortly after founding the Rein Abbey.

After his death, Sophia continued to fund the building of the abbey.

She and Bernard of Trixen served as co-regents over the March of Styria until her son came of age in 1139.

In her later life she took religious vows and joined the Admont Abbey.