Sophie, Baroness De Schaepdrijver (b. Kortrijk, 11 September 1961) is a Belgian historian.
From 1986 until 1988, de Schaepdrijver was assistant professor at the department of history of the Free University of Amsterdam.
From 1988 until 1990, she worked as a dissertation fellow at the Amsterdam School for Social Science Research.
She left for the United States in 1995, where from 1995 until 1996, she was a fellow at the National Humanities Center, Research Triangle Park, N.C. .
Since 2001, she is associate professor of modern European history at the Pennsylvania State University.