She was regent of Jülich, Berg and Ravensberg during the incapacity of her spouse and the minority of her eldest son William IV from 1456 until 1473.

In 1444, she married Duke Gerhard VIII of Jülich-Berg, Count of Ravensberg (born: 1416 or 1417; died: 1475).

In approximately 1456, Gerhard lapsed into insanity and was incapable of ruling.

Sophie took over the reins of government in the Duchy as regent, since her firstborn son, who would otherwise have been considered for the regency, was himself a minor.

Her sons responded by besieging his Tomburg Castle and setting it on fire.