Sose Mayrig (Armenian: Սօսէ Մայրիկ, 1868 – 1953), born Sose Vartanian, (Սօսէ Վարդանեան) was an Armenian female fedayee, the wife of the famous Aghbiur Serob.

She was surnamed "mayrig" (mother) by Serop's hajduks for her bravery and maternal concern for Armenian youth.

In 1898, after the battle of Babshen, Sose and Serop fled to Sassoun.

Another son of Sose Mayrig and Serop was killed during the massacre in Erzerum.

From 1920, Sose Mayrig lived in Constantinople, then in Alexandria (Egypt), where she died in 1953.