Established in 1997, South Granville (or less commonly "Uptown") is an upscale Business Improvement Area (BIA) and neighbourhood south of Vancouver's downtown core, centred along Granville Street and bordered by the neighbourhoods of Kitsilano, Fairview and Shaughnessy.

Separated from Downtown by False Creek, the area runs along Granville Street from the south side of the Granville Street Bridge up to 16th Ave, where storefronts are replaced by the residences and hedges of Shaughnessy.

In that year Richard Marpole drew up plans for Shaughnessy Heights, the Canadian Pacific Railway's newest subdivision south of 16th Ave, pitched as an alternative to the then-upscale West End ("Blueblood Alley").

In 2007, the South Granville BIA commemorated the neighbourhood's centennial by encasing a state-of-the-art, stainless steel time capsule in concrete and stone under the entrance of the historic Stanley Theatre.

As well as being a fast-growing neighbourhood of residences, shops and restaurants, South Granville is home to a vibrant arts and culture scene.