Originally the southern section of La Brea Avenue within Inglewood was named Commercial Street.

The southern terminus of La Brea Avenue is at its intersection with Century Boulevard in Inglewood.

It is a continuation of Hawthorne Boulevard in the South Bay area of Los Angeles County.

It also passes through the eastern low Baldwin Hills mountain range, by Kenneth Hahn State Recreation Area and the remnant Inglewood Oil Field.

An elevated light rail station for the Metro E Line is located at the intersection with Exposition Boulevard in the West Adams neighborhood.