South Quay is a Docklands Light Railway (DLR) station on the Isle of Dogs, East London, England.

The DLR's plan to operate 3 unit trains on this line therefore included the relocation of this station to a new site over Millwall Dock some distance to the east, resulting in the relocated station partly being in Cubitt Town.

They would need to be lengthened by thirty metres for three-unit trains but the curves either side of the station precluded extension work.

A small shopping centre, South Quay Plaza, is across the road from the station.

The South Quay Footbridge provides a connection to the Canary Wharf private estate.