South Terrebonne High was officially opened in 1961, with the first graduating class commencing in 1962.

[2] Prior to 1988, South Terrebonne housed students in their sophomore, junior, or senior year.

Today, the school houses over 1,000 students in grades 9-12, with 8th graders added in special education or advanced gifted classes.

From 2015 to 2016 the Louisiana State Department of Education score for this school increased from 88.8 to 108, meaning the ranking improved to an "A" level.

[3] South Terrebonne competes in District 7 of Class AAAA (4A), the second highest classification of athletics in the LHSAA.