The team competes in the NCAA Division I Football Championship Subdivision (FCS) and are members of the Ohio Valley Conference.

[4] In 1991, Southeast Missouri State joined the Ohio Valley Conference and moved up to the Division I-AA level.

Southeast Missouri State has won 21 conference championships, 12 outright and nine shared.

[5][6] † Co-champions The Redhawks have made five appearances in the Division I–AA/FCS playoffs, with a combined record of 1–5.

[9] In 2013, the two schools played in a game called the College Classic, at Busch Stadium in St.