Wilkerson was a member of the Southeast Missouri State Redhawks for five seasons, redshirting as a true freshman.
[1] As a redshirt senior, he caught 71 passes for 1,350 yards and 10 touchdowns and was named first-team All-Ohio Valley Conference and a second-team All-American by HERO Sports.
[2] Wilkerson finished his collegiate career with 219 receptions for 3,540 yards and 33 touchdowns, all of which were school records.
[3] Wilkerson was signed by the Tennessee Titans as an undrafted free agent on May 4, 2020.
[11] On January 2, 2022, Wilkerson was elevated for the Week 17 game against Jacksonville and scored his first two NFL touchdowns.