Southern Hospitality focuses on the careers and personal lives of the staff at Leva Bonaparte's restaurants and bars.

The series is primarily centered around Republic Lounge & Garden, but occasionally features Bonaparte's other property Bourbon and Bubbles Restaurant & Bar.

The original cast consisted of: Bradley Carter, Emmy Sharrett, Grace Lilly, Joe Bradley, Lucía Peña, Maddi Reese, Mia Alario, Mikel Simmons, TJ Dinch, Will Kulp, and Leva Bonaparte as series regulars.

[4] The third season premiered on January 2, 2025, with Molly Moore, Michols Peña, Lake Rucker and Austin Stephan joining the cast as new series regulars.

[5] Writing for Common Sense Media, reviewer Melissa Camacho said, "While the overall series will remind you of unscripted shows like Vanderpump Rules, Southern Hospitality remains true to its roots by attempting to contextualize all of this within Southern culture and community, a few of which border on stereotypes about women, clothes, and attitudes.