Competitors have represented Spain in ten of the twelve Summer Paralympics, missing only the first two events in Rome and Tokyo.

Spain's breakthrough year came in 1992 when they hosted the event; their medal tally rocketed with a level of performance that would be maintained for the following two events.

The 2000 Summer Paralympics in Sydney saw their greatest achievements at the Games but the medal victories were overshadowed by a cheating controversy that would change the way that intellectually disabled competitors were tested for their disability (see Cheating at the Paralympic Games).

At the same time, women have won 48.39% of all Spain's Paralympic medals compared to 24.32% for men.

Years in Italics mean the athlete participated but did not win any medal.