The hospital is a subsidiary of University of Michigan Health - Sparrow, and is affiliated with the Colleges of Human Medicine and Osteopathic Medicine at nearby Michigan State University.

[1] University of Michigan Health - Sparrow Lansing operates the only dedicated pediatric and adult emergency department in the region.

The emergency department is a level I trauma center, as verified by the American College of Surgeons.

University of Michigan Health - Sparrow Lansing was founded in 1896, when the Women's Hospital Association supported one doctor and one nurse out of a rented house.

Breast cancer survivor Judi Herbert, who along with her husband, Jim, and Dr. James and Susan Herman, donated a combined $2.5 million to the development of the center.