is a five-mile (8.0 km) loop through the eastern Pittsburgh suburbs of Churchill, Wilkins Township, and Monroeville, Pennsylvania, on William Penn Highway.

The route was the former pathway of US 22 itself before the construction that extended I-376 from this point eastward to the Pennsylvania Turnpike, in the early 1960s.

The remaining three miles (4.8 km) feature dense commercial development, including several office high rises and Monroeville Mall.

The highway ends at a complicated junction that features the northern terminus of Pennsylvania Route 48 (PA 48), the southern end of Haymaker Road, and I-376, which features its last two exits (before the Pennsylvania Turnpike) with the above streets.

then travels for its final eighth of a mile (0.201 km) on a viaduct that allows for connections with the Pennsylvania Turnpike and a smooth transition on to US 22 east (continuing William Penn Highway) toward suburban Murrysville.

It serves as the major through street, taking on the former designation of its parent, which has become a freeway bypass.

The last two miles (3.2 km) wind along the Juniata River toward the eastern freeway juncture in Derry Township.

[1] On June 29, 1978, the American Association of State Highway and Transportation Officials (AASHTO) approved the removal of the US 22 Byp.

designation; the route was replaced by US 22 along Arsenal Boulevard and Herr Street.

was an alternate route of US 22 that ran between the cities of Bethlehem and Easton in Pennsylvania between the 1930s and 1950s.

The route continued east to Wilson, where it came to its eastern terminus at US 22 (Butler Street).

The route began at the Northampton Street Bridge over the Delaware River to Easton, Pennsylvania.

became concurrent with Route 28 and ran through Phillipsburg on South Main Street and Pohatcong Township on New Brunswick Avenue before ending at US 22.

was the designation for a bypass of the segment of US 22 through the downtown areas of Easton, Pennsylvania, and Phillipsburg, New Jersey, between the 1930s and 1940s.

turned southeast along Route 24-28 Link to end at US 22/Route 28 in Pohatcong Township.