The film was directed by Nick Lyon and starring Ben Cross, Helena Mattsson, Dominic Keating and Marlene Favela.

Tom tells Miranda she is the result of an experiment that combined human and alien DNA, conducted with his friend Forbes McGuire while they were in college.

In Mexico, Tom and Miranda locate Forbes, who lives with his recent experiment, Azura, another human and alien DNA hybrid who serves as his assistant and lover.

Forbes supports his experiment by creating half-alien facsimiles of dead pets and relatives for paying clients.

Tom checks her blood as she invites him to get drunk and have sex in their hotel room; he tells her to rest, believing she is delirious from the procedure.

Tom finds Forbes did a sloppy job; Miranda's hormones are unstable, causing her alien side to become increasingly dominant.

Driven by her alien sex drive, Miranda seduces the innkeeper, another hybrid, but she kills him mid-process upon finding he is sterile.

Tom takes Miranda back to Forbes' house, where he discovers via X-ray that a hybrid child is rapidly growing in her womb.

[1] The producers wanted to go back to H. R. Giger's designs of the alien creature due to popularity with fans and the absence of this decision in the last installment.

[citation needed] The original look is apparent but with different color variations and new spikes on the aliens' wrists of the nemesis.

[citation needed] It is also the first in the series that a half-human, half-alien character does not change fully into the alien creature but has prosthetic eyebrows, veins and contacts for a long period of time in more than one scene.