In August 2000, Richard C. Breon was hired to lead the organization as CEO, and sought to form an integrated health care system.

[9] In 2022 Beaumont and Spectrum announced their merger was effective on February 1, 2022, because the federal government determined this would not violate antitrust regulations.

Spectrum Health has an air ambulance helicopter service, called Aeromed, that transports patients between accident scenes as well as between hospitals and the airport.

[12][13] Spectrum Health Visiting Nurses Association provides home care services in the West Michigan area.

It was developed to bring all cancer research and patient service delivery under one roof in the Spectrum Health System.