The land for the project was purchased in 2002 with a donation from Frederik and Lena Meijer.

The $78 million facility, with some 284,000 square feet (26,400 m2) over six floors, opened on June 30, 2008.

[1] The Pavilion is named after two employees that worked for Meijer and advanced their way to the top of the company.

It contains the only adult blood and marrow transplant department in West Michigan.

[3][4] During the COVID-19 pandemic, the center offered drive-up options for some cancer treatements, although chemotherapy was still carried out inside the clinic.