It features the return of the Jackal and the Queen (Adrianna "Ana" Soria) to the Marvel Universe and laid the ground work for the second volume of the Scarlet Spider series.

The main story overall received positive reviews, with critics praising its action, humor, style, and plot.

He puts in some time at Horizon Labs; finally, he visits Shang-Chi, his martial arts mentor who is teaching him "The Way of the Spider", as seen in the Free Comic Book Day edition of The Amazing Spider-Man.

[3] Although Shang-Chi is able to confirm Spider-Man's identity to the other heroes, he is nevertheless ordered to stay out of the fight due to the inability to distinguish him from the other Spider-Men.

However, inspired by a conversation with Mary Jane, Peter is able to rally various other New Yorkers to help him stop the villainous Spider-Men by posing as just another random spider-powered citizen like them.

Meanwhile, Carlie and Peter attempt to investigate the Jackal's lab, reasoning that he is the most likely candidate to have caused this event, unaware that they are being watched.

[4] Horizon Labs works with Reed Richards to find a cure for the spider-powered people while the Avengers and other heroes try to keep Manhattan quarantined.

While at an abandoned lab at Empire University, Peter and Carlie are attacked by Chance, Scorcher, and White Rabbit, who all have spider powers.

[6] Despite Jackal's contrary advice, Reed Richards and Horizon Labs manage to develop a serum from Anti-Venom's symbiotic antibodies, able to kill the Spider-Virus and instantly reverse the mutations.

As Tarantula, now more physically powerful and still enabled with a functioning Spider-Sense, starts gaining the upper hand, Reed Richards mentions to the Horizon Labs scientists how Spider-Man lost his special sense.

The Horizon Lab scientists manage to jury-rig a counter-frequency, restoring Peter's Spider-Sense to an enhanced level (due to Shang-Chi's kung fu training being merged to his reflexes).

Spider-Queen uses an evolved version of her sonic scream to kill Jackal (later revealed as yet another clone), and realizes she has been given the whole powers of the Web, becoming a Spider-Goddess.

Kaine, Mary Jane and Spider-Man join the fight, as the whole heroic community of New York tries to prevent Spider Queen and Madame Web's apocalyptic prophecy.

While Mary Jane bravely defends him, Peter uses the antenna on the Empire State Building to reverse the mutation of a large part of New York's population at once.

Emboldened by Spider-Man's example and seeing Spider-Queen losing her powers, Kaine has himself thrown in her mouth using the Spider-Armor to deflect the sonic scream and spider-stingers (similar to the ones held by Peter Parker during The Other) to slay the Spider Queen.

The Jackal, in disguise as part of Damage Control, harvests some of the deceased Queen's marrow for use in future cloning experiments.

[8] The following day, Peter discovers from Doctor Strange that the psychic blindspot that was put in place to protect his secret identity has now been compromised.

Mary Jane tells Peter to look at the Empire State Building, onto which is projected a red and blue color scheme.

Madame Web tells Spider-Girl she will need to team up with her "enemy" when the Sisterhood's leader All-Mother plans to release a poison that will kill anyone with spider powers.

Frog-Man witnesses terrorists with spider powers attacking the United Nations and gains the assistance, and eventual grudging respect, of Ms. Marvel, Jessica, and Hawkeye.

While stopping the people dressed as Spider-Man, Cloak and Dagger recall the time they worked for Norman Osborn's Dark X-Men.

When he sees Iron Fist fighting the Spider-Man imposters and Peter Parker nearby, Shang-Chi springs into action.

[18] When trying to figure out what his recurring dream means, Shang-Chi learns from Silver Sable that she has found possible locations in Manhattan for Bride of Nine Spider's lair.

Although Shang-Chi manages to defeat Bride of Nine Spiders and frees Iron Fist, he discovers that the person behind this is the demon Ai Apaec who seeks to feed off the Immortal Weapons.

After making sure Iron Fist and the rest of the Immortal Weapons are evacuated, Shang-Chi collapses the mansion hide-out on Ai Apeac, leaving him immobilized for the Avengers to put back into custody.

They end up fighting spider-powered versions of Flashmob (Chemistro III, Cheshire Cat, Commanche, Dontrell "Cockroach" Hamilton, Mr.

[21] When the civilians who gained spider powers start to turn into half-spider creatures, Spider-Woman is fighting some of them while Mister Fantastic states in the communication that HYDRA once used a corrupted version of her DNA on Alicia Masters as part of their super-soldier experiment.

[24] When the people of Manhattan start developing spider-powers, Venom is sent in to capture a spider-like beast that is fighting Firestar and Gravity.

They take down the Queen, but she transforms into a bigger, stronger spider form and is taken down by Venom, Rogers, Spider-Man, Kaine, and the assistance of the Avengers.

[29] According to Comic Book Roundup, Amazing Spider-Man Issue 667 received an average score of 7.7 out of 10 based on 9 reviews.