Spine is a biweekly peer-reviewed medical journal covering research in the field of orthopaedics, especially concerning the spine.

It was established in 1976 and is published by Lippincott Williams & Wilkins.

The current editor-in-chief is Andrew J. Schoenfeld, M.D.. Spine is considered the leading orthopaedic journal covering cutting-edge spine research.

Spine is available in print and online.

Spine is considered the most cited journal in orthopaedics.