Spirito Santo, Cortona

The Church of the Holy Spirit or Chiesa dello Spirito Santo is a 17th-century, Roman Catholic church built just outside the medieval walls of Cortona, region of Tuscany, Italy.

The site had previously housed an aedicule with a miraculous icon of the Virgin.

The church was occupied by priests of the order of the Congregation of St Elizabeth.

An inventory in 1900 described the main altar and the sculptures are the work of Francesco Fabbrucci (1687–1767), who also created the statues of Faith and Charity, which are copies of the statues by Bernini on the tomb of Pope Urban VIII.

In the altar on the right is a canvas depicting the Madonna with Infant Jesus, Santa Margherita and San Felice by Giuseppe Angeli.