Spokane (/spoʊˈkeɪn/ spoh-KAYN) is a census-designated place in Christian County, Missouri, United States.

[7] According to the United States Census Bureau, the CDP has a total area of 0.84 square miles (2.18 km2), all land.

There were 64 housing units at an average density of 76.2 per square mile (29.4/km2).

8.9% of all households were made up of individuals, and 3.6% had someone living alone who was 65 years of age or older.

7.9% of all households were made up of individuals, and 5.3% had someone living alone who was 65 years of age or older.

The local business association is the Spokane/Highlandville Chamber of Commerce, denoting the strong link the communities of Spokane and Highlandville to the north.

Spokane has fewer residents and encompasses less area than Highlandville, but is the main location for the local public junior high and high schools, and has more commercial structures and businesses.