The series is filmed inside a Los Angeles airport hangar or on location using a mobile laboratory.
Each episode on season 1 focused on testing certain aspects of athletics (such as human flight and reaction time), while season 2 either poses more questions from previous episodes, or tries to re-analyze sporting moments or trials and tribulations, puts a human against animals or machines, or even checking against other sports or challenging the odds with data gathered using motion sensors and accelerometers.
Professional athletes are featured prominently and are used to test the limits of the human body.
In addition, host John Brenkus also participated in cases where an "average Joe" was required.
Using methods that have been developed to understand human injury biomechanics, and developing new techniques to address the unique challenges found when studying live volunteers in high impact and high speed activities, Dr. Bir helps viewers to understand the forces (internal and external) sustained and generated by the body during high level athletic activities.