A squamous cell papilloma is a generally benign papilloma that arises from the stratified squamous epithelium of the skin, lip, oral cavity, tongue, pharynx, larynx, esophagus, cervix, vagina or anal canal.

[1][2][3][4] Squamous cell papillomas are typically associated with human papillomavirus (HPV) while sometimes the cause is unknown.

Oral papillomas are usually painless, and not treated unless they interfere with eating or are causing pain.

[1] Normally found in children or young adults, a common cause of conjunctival squamous cell papilloma is during childbirth, when the mother passes the virus to her child.

[9] While most cases require no treatment, therapy options include cryotherapy, application of a topical salicylic acid compound, surgical excision and laser ablation.