The school was the inspiration of the Father James J. Behan, the first formal pastor of the adjoining church of the same name, Ss.
It opened in September 1962, staffed initially by the Sisters of Saint Joseph from Brentwood, New York.
The Sisters were associated with the original mission church in Deer Park when they instructed Sunday school.
Cyril and Methodius consecrated its first sanctuary in 1934[citation needed], receiving its patrons by settlers to the area of Slovak origins.
Famous alumni include LeRoy Homer, the co-pilot of United Airlines Flight 93, and C. J. Ramone.