The Cathedral sits at what was the western edge of the town's almshouse that survived until the sixteenth century.

Opened on 7 August 1836, it is the oldest Catholic Church in Dundee, and has a seating capacity of about 1,000.

[1] The halls in the basement served for years as the only Catholic school in the city.

The sanctuary (presbyterium) area, which contains the high altar and stalls for the canons of the cathedral, was added later by knocking out the back wall and building on top of the clergy house.

As in all Catholic churches, the cathedral has a set of the Stations of the Cross on the walls.