St. Andrews is a census-designated place (CDP) in Richland County, South Carolina, United States.

[5] It is part of the Columbia, South Carolina Metropolitan Statistical Area.

The Pine Grove Rosenwald School was listed on the National Register of Historic Places in 2009.

[5] As of the 2020 United States census, there were 20,675 people, 9,534 households, and 4,364 families residing in the CDP.

40.5% of all households were made up of individuals, and 5.6% had someone living alone who was 65 years of age or older.