St. Charles is a city in Winona County, Minnesota, United States.

[6] The city was evacuated on April 17, 2009, when a large fire at North Star Foods, a poultry processing plant, threatened anhydrous ammonia tanks.

[9] Three properties in St. Charles are listed on the National Register of Historic Places: the 1874 Trinity Episcopal Church, the 1876 St. Charles City Bakery, and the 1890s Whitewater Avenue Commercial Historic District.

[10] According to the United States Census Bureau, the city has a total area of 3.86 square miles (10.00 km2), all land.

[11] U.S. Highway 14 bisects the city from east to west, as does the Dakota, Minnesota and Eastern Railroad.

Minnesota State Highway 74 goes through the city from south to north, running along Whitewater Avenue, also known as Main Street.

26.2% of all households were made up of individuals, and 12.5% had someone living alone who was 65 years of age or older.

It honors the late Carl H. Fischer, a local resident who developed many varieties of that flower.

Fischer created a business called Noweta Gardens which developed hundreds of different varieties of Gladiolus.