[4][5] In 1740, the ecclesiastical parish and chapel relocated to the present-day site of the church on the eastbank of the Mississippi River.

[6] The log cabin chapel built in 1740, burned in 1806 and was replaced by a wood-framed church painted red during that same year.

[7] In 1917, a parochial charter was adopted and St. Charles Borromeo ecclesiastical parish was reinstated to the diocese by Archbishop James Blenk.

The altar stone of the church rests on a walnut tree trunk imported from Arona, Italy.

The tree is estimated to be four-hundred years old and dates back to the time Charles Borromeo was in Arona, Italy (16th century).

[11] Charles Frederick d'Arensbourg, leader of the German Coast, is buried in the cemetery, but his grave was lost due to the shifting Mississippi River.

Louisiana state senator Jean Noël Destréhan, who died in 1823, is buried in the cemetery, but his grave was also lost due to the shifting Mississippi River.