St. Elizabeth's Medical Center (abbreviated SEMC, also known locally as St. E's) is a mid-size non-profit teaching hospital located in the Brighton neighborhood of Boston, Massachusetts.

[3] Established to primarily attend to medical needs specific to the poor and elderly women of Boston, the hospital was an early pioneer in the field of gynecology.

[4] In 2010, St. Elizabeth's was converted into a for-profit hospital when its parent organization, Caritas Christi Health Care, was purchased from the Archdiocese of Boston by private equity firm Cerberus Capital Management, becoming one of the original members and the flagship hospital of the newly created Steward Health Care System.

[7] Steward sold much of their hospitals' real estate, including that of St. Elizabeth's, to real estate investment trust Medical Properties Trust in 2016 in a sale-leaseback deal, providing the hospital system with $1.25 billion used both to pay hundreds of millions of dollars in dividends to investors[8] and to fund a nationwide expansion of the healthcare system.

In December 2023, St. Elizabeth's was sued by the Department of Justice for violations of the False Claims Act and Stark Law in regards to allegations of improper referrals and Medicare billings from its cardiac surgery program.

[13] Amid these financial difficulties, Steward Health Care in January 2024 informed state lawmakers of its intention to sell at lease four of its Massachusetts hospitals to other operators, including St.

[14] On May 5, 2024, The Wall Street Journal reported that Steward Health Care was expected to file for Chapter 11 bankruptcy protection within the coming days, blaming rising costs, insufficient revenue and cash crunches as part of the decision.