The hospital was founded in 1909 by the Catholic organization Sisters of Charity of Leavenworth.

[2] Since 2006, KTPK has done a radiothon for the Children's Miracle Network Hospitals (CMN) at St. Francis Health Center in Topeka, Kansas.

The radiothon takes place at Topeka's West Ridge Mall, each year during a week in August, on a Tuesday through Thursday from 6 AM to 6 PM.

While on air, they not only raise money for the sick and injured children, but tell stories, as well.

The Radiothon is the largest fundraiser of the year for the local CMN.