Noble County's pioneer settlers arrived soon after the Treaty of Greenville, 1795;[2]: 117  although the area is near the earliest settlement at Marietta, the northward advance of civilization was delayed by events such as the Big Bottom massacre, 1790, on the Muskingum River not far to the west.

No longer did the village's Catholics need to await occasional visits from the priest at Immaculate Conception Church in Fulda in order to hear Mass.

The primary portion of the church is a simpler rectangular structure; the shingled roof rises to a prominent gable at the front of the building.

One of Ohio's most rural areas, Noble County possesses a built environment consisting primarily of traditional vernacular buildings, rather than the high style and professional craftsmanship that the church exemplifies.

The property is one of nine Noble County locations on the National Register; among the others is Immaculate Conception Church in Fulda,[1] which supported Harriettsville's Catholics before St. Henry parish was formed.