The school is named after St. Hubert, the patron saint of hunters, and is under direction of the Archdiocese of Philadelphia.

From circa 1997 to 2012 the enrollment declined by 55%, the sharpest decrease of any senior high school in the Philadelphia archdiocese, and in 2012 the campus was 40% occupied.

The Archdiocese of Philadelphia used the lower enrollment and a budget shortfall of $624,480 from 2006 to 2012 as reasons to have the campus closed.

St. Hubert also has experienced many athletic accomplishments and has won some championships over the years, including tennis, bowling, and soccer.

The 2022-23 Saint Hubert Varsity and JV Gold Cheerleading won first place at the NCA competition.