[1] The school teaches curriculum based on the Catholic faith, and has close ties with the Diocese of Hamilton and the local church, St. Matthew's Parish.

In addition to over 46 varsity sports teams, the school is home to dozens of clubs of various disciplines.

Loyola also provides opportunities for its students to participate in regional activities, such as the Southern Ontario Model United Nations Assembly (SOMA).

Recently, particular emphasis has been placed on the Loyola athletics program, with the school holding numerous buyouts and pep rallies in order to drum up support for various sports teams.

Additionally, since 2007, the school has upgraded numerous sports facilities at the school, including replacing the gymnasium floor, purchasing electronic bleachers for spectators and spending over $2 million on a new sports field, which is now completed.