St. John's Leprosy and HIV Care Services is a charitable undertaking of the Major Archieparchy of Trivandrum of the Syro-Malankara Catholic Church.
In the early 1960s, there was a leprosy clinic at Koppam run by the Church of South India.
In the beginning of 1963, Miss Dunn was looking for some agency to carry out the work and she met late Archbishop Benedict Mar Gregorios.
St.John’s Hospital was formally inaugurated on 15 February 1964 by Health Minister Mr. Willington and the late Archbishop Benedict Mar Gregorios.
In 1999, the Leprosy & TB Control Program was launched at Trivandrum City Corporation under the leadership of this Hospital.