[1] During construction, a storm approached the city from Lake Erie and destroyed several homes in the area.

In 1902, Bishop James Quigley decided that the diocese required a new cathedral and purchased property at Delaware Avenue and Utica Street beginning in 1902.

Italian architect Aristide Leonori designed a new Gothic Revival cathedral which was constructed between 1912 and 1915.

[2] The exterior marble started to separate from the brick and Bishop Edward D. Head determined in 1976 that repairs would be too costly for the "new" St. Joseph's and the diocese.

[3] Bishop Timon selected New York architect Patrick C. Keely, who had worked with A. W. N. Pugin, to design the church.

The three lancet windows above the altar were produced at the direction of King Ludwig II of Bavaria for the Paris Exposition of 1855.

In 1998, the bishop and parish council engaged the Andover Organ Company to restore and expand the instrument.