The John F. Lutz Furniture Co. & Funerary buildings was added to the National Register of Historic Places in 1996.

[5] It is bordered by the borough of Mount Penn to the west and by Exeter Township to the north, east, and south.

(West Reading) The unincorporated communities of Pennside, Jacksonwald, and Reiffton border the borough on the northwest, east, and south, respectively.

According to the United States Census Bureau, St. Lawrence has a total area of 0.9 square miles (2.3 km2), all land.

PA 562 follows St. Lawrence Avenue from its western terminus at US 422 Business eastward through the heart of the borough, leading east to Boyertown.

Incorporated in 1927, the borough is named for the St. Lawrence Woolen Mill, founded by William Brumbach, which once operated in town.

The Oley Turnpike ran through the town, which was the last privately owned toll road in Pennsylvania.