The parish was established January 5, 1829 with land contributed by Louis Stephen LeCouteulx de Caumont ([1]), a French nobleman.

In 1837, the Irish members left to establish St. Patrick's Church, at Washington and Clinton.

In 1846 a large group of the French congregants withdrew to form their own parish.

Among the German parishioners left were prosperous and highly respected businessmen.

The church is laid out in a Latin-cross floor plan and features a 245 ft octagonal Medina sandstone steeple with a Seth Thomas clock.